Alnylam Pharmaceuticals, Inc. · XNAS · 131 sessions on record
$246.74▼ −7.33 · −2.9%from $254.07 the session before · Sep 30, 2026 close · end of day
Open
$253.68
High
$254.44
Low
$246.66
Day's range
$7.83.1% of the previous close
VWAP
$249.12close −0.96% from it
Volume, shares
1.04M0.69× the 20-session average
Traded, $
$260.2M
Trades
28.1K37 shares per trade
Previous close
$254.07−7.33 to the close
Market cap
$33.02Bat the close of Sep 30
Day range1% of the way up
$246.66$254.44
52-week range27% of the way up
$197.81 Jul 30$380.00 Jul 9
−35% from the high · +25% from the low
Options
No listed options on ALNY
Close $ · S&P 500 rebased to the first close126 sessions to Sep 30 · axis fixed at 4 × ATR-14 around the last close · hover or tap a session and the read beside the chart follows it
Revenue $1.29B, +67% on a year earlier; profit $164.5M in the Jun 2026 quarter, consolidated.
Last 8 quarters, consolidatedUS dollars as filed · year on year against the same quarter a year earlier · market: close on the first session after the filing against the last close before it, S&P 500 over the same session
Quarterly results of ALNY on the consolidated basis with the market's move on the first session after each filing
Quarter
Revenue $
Revenue YoY
Profit $
Profit YoY
EPS $
Market on the day
Jun 2026filed Jul 30
$1.29B
▲ +67%
$164.5M
—
1.21
0.0%S&P 500 +0.7% · −0.7 pp
Mar 2026filed Jul 30
—
—
$206.0M
—
—
0.0%S&P 500 +0.7% · −0.7 pp
Dec 2025filed Feb 12
$1.10B
▲ +85%
$153.1M
—
1.18
—not reached
Sep 2025filed Oct 30
$1.25B
▲ +150%
$251.1M
—
1.84
—not reached
Jun 2025filed Jul 30
$773.7M
▲ +17%
−$72.2M
—
-0.55
0.0%S&P 500 +0.7% · −0.7 pp
Mar 2025filed Jul 30
$594.2M
▲ +20%
−$18.3M
—
-0.14
0.0%S&P 500 +0.7% · −0.7 pp
Dec 2024filed Feb 13
$593.2M
▲ +35%
−$83.8M
—
-0.66
—not reached
Sep 2024filed Oct 30
$500.9M
▼ −33%
−$111.6M
▼ −180%
-0.87
—not reached
By fiscal yearfiscal years as filed in the 10-K · named by the year the fiscal year ends
Financial-year results of ALNY on the consolidated basis, summed from the quarters filed
Year
Revenue $
Revenue YoY
Profit $
Profit YoY
EPS $
FY25to Dec 2025
$3.71B
▲ +65%
$313.7M
—
2.33
FY24to Dec 2024
$2.25B
▲ +23%
−$278.2M
—
-2.18
FY23to Dec 2023
$1.83B
▲ +76%
−$440.2M
—
-3.52
FY22to Dec 2022
$1.04B
▲ +23%
−$1.13B
—
-9.30
FY21to Dec 2021
$844.3M
▲ +71%
−$852.8M
—
-7.20
Fundamentals
consolidated · filings to Jun 2026 · close $246.74 on Sep 30
24 times book value, market cap $33.02B.
Valuation
Market cap
$33.02Bon Sep 30
Price to earnings
—
Trailing EPS
—
Price to book
24consolidated · balance sheet to Jun 2026
Book value a share
$10.12consolidated · balance sheet to Jun 2026
Debt to equity
—
Return on equity
81%trailing profit over average equity · consolidated
Dividend yield
—
Price to sales
—
Shares outstanding
134Mon Sep 30
Growthsums of the four quarters filed to Jun 2026 · growth against the four quarters before them · consolidated
Revenue, trailing 12 months
—
Revenue growth, 12 months
—
Revenue 3-year CAGR
—trailing twelve months against the twelve months 3 years earlier · consolidated
Profit, trailing 12 months
$774.7Mfour quarters to Jun 2026
Profit growth, 12 months
—
Profit 3-year CAGR
—
Shareholding
quarter to Jun 2026 · SEC Form 13F
13F managers hold 190% of shares, FMR LLC the largest at 22%, Capital World Investors 17% and BlackRock, Inc. 16%, as filed for the quarter to Jun 2026.
22.5%16.7%16.3%133.5%
FMR LLC 22.5%
Capital World Investors 16.7%
BlackRock, Inc. 16.3%
Other 13F managers 133.5%
Held by 13F managers
190%of shares outstanding
Shares held
253M+3.9% on Mar 2026 among managers filing both
Managers holding
744747 a quarter earlier
Largest holder
22%FMR LLC
Largest 10 holderspercent of shares outstanding · change in shares against the previous quarter
Largest 13F holders of ALNY
Manager
Shares
Of outstanding
Value
Change on quarter
FMR LLC
30M
22%
$9.05B
+890K
Capital World Investors
22.3M
17%
$6.71B
+685K
BlackRock, Inc.
21.8M
16%
$6.57B
+926K
Capital Research Global Investors
19.5M
15%
$5.87B
+559K
VANGUARD PORTFOLIO MANAGEMENT LLC
13.1M
9.8%
$3.94B
+94.2K
VANGUARD CAPITAL MANAGEMENT LLC
12.1M
9.0%
$3.63B
+166K
Invesco Ltd.
7.51M
5.6%
$2.26B
+4.93M
STATE STREET CORP
7.11M
5.3%
$2.14B
+466K
JPMORGAN CHASE & CO
5.35M
4.0%
$1.57B
—
GEODE CAPITAL MANAGEMENT, LLC
5.27M
3.9%
$1.58B
−49.1K
Insider tradesSEC Forms 3, 4 and 5 · the latest 10
No open-market insider buying or selling in the last 90 days.
ALNY insider trades
Insider
Trade
Shares
Price
Held after
PYOTT DAVID E IDirector
sold · Jun 1, 2026
1,175
$298.91
3,316
PYOTT DAVID E IDirector
sold · Jun 1, 2026
17
$302.65
1,582
PYOTT DAVID E IDirector
sold · Jun 1, 2026
921
$297.71
4,491
PYOTT DAVID E IDirector
sold · Jun 1, 2026
495
$300.72
1,599
PYOTT DAVID E IDirector
exercised · Jun 1, 2026
3,830
$0.00
5,412
PYOTT DAVID E IDirector
sold · Jun 1, 2026
1,222
$299.87
2,094
Arbuckle Stuart ADirector
granted · May 20, 2026
671
$0.00
671
Ausiello Dennis ADirector
granted · May 20, 2026
671
$0.00
1,582
BRANDICOURT OLIVIERDirector
granted · May 20, 2026
671
$0.00
1,446
HAMBURG MARGARET ADirector
granted · May 20, 2026
671
$0.00
1,582
Corporate actions
exchange records
No corporate action on record for ALNY yet.
Price history
131 sessions on record · to Sep 30 · end of day
ALNY is +0.3% over 20 sessions against the S&P 500's +0.1%, 35% below its 52-week high, realised volatility 47% annualised.
Returns against S&P 500longest window first · S&P 500 over the same sessions
Returns of the stock and S&P 500 over six windows, longest first
Window
From $
ALNY %
S&P 500 %
Difference pp
120 sessionssince Apr 9
$321.28
▼ −23%
▲ +12%
−35
60 sessionssince Jul 7
$321.57
▼ −23%
▲ +2.0%
−25
20 sessionssince Sep 1
$246.10
▲ +0.26%
▲ +0.11%
+0.15
5 sessionssince Sep 23
$246.52
▲ +0.09%
▼ −0.67%
+0.76
1 sessionsince Sep 29
$254.08
▼ −2.9%
▼ −0.21%
−2.7
Averages of the closeclose against each average
5-session average
$252.34close −2.2% from it
20-session average
$251.46close −1.9% from it
50-session average
$243.19close +1.5% from it
Range and volumetrue range over 14 sessions · high to low over 20 · volume against the 20-session average
Average true range, 14
$8.33.4% of the close
Average day's range, 20
$9.53.8% of the close
Volume against 20 sessions
0.69×1.04M vs 1.46M average
Volatility and co-movement with S&P 500annualised from daily returns
Realised volatility, 20
47%≈ ±2.9% a session · moved more than that on 4 of 20
Realised volatility, 60
82%≈ ±5.2% a session · moved more than that on 7 of 60
Beta to S&P 500, 60
-0.65moved with S&P 500 on 34 of 60 sessions
Up and down sessionscloses above and below the previous close
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