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PYXS

Pyxis Oncology, Inc. Common Stock · XNAS · 131 sessions on record
$2.33▼ −0.57 · −19.7%from $2.90 the session before · Sep 30, 2026 close · end of day
Open
$2.38
High
$2.41
Low
$2.12
Day's range
$0.2910% of the previous close
VWAP
$2.27close +2.8% from it
Volume, shares
8.15M8.78× the 20-session average
Traded, $
$18.5M
Trades
26.6K310 shares per trade
Previous close
$2.90−0.57 to the close
Market cap
$194.3Mat the close of Sep 30
Day range72% of the way up
$2.12$2.41
52-week range37% of the way up
$1.26 Mar 30$4.15 Sep 8

−44% from the high · +85% from the low

Options

No listed options on PYXS

Close $ · S&P 500 rebased to the first close126 sessions to Sep 30 · axis fixed at 4 × ATR-14 around the last close
131 sessions on file · from Mar 25
PYXS close over the last 126 sessions, with S&P 500 rebased to the first close1.382.633.89axis spans 182%S&P 500PYXSApr 1Jul 2Sep 30126 sessions from Apr 1 to Sep 30; the price axis spans 182 percent.

Quarterly results

consolidated · latest filed Aug 13, 2026 · SEC filings

Profit −$25.3M in the Jun 2026 quarter, consolidated.

Last 8 quarters, consolidatedUS dollars as filed · year on year against the same quarter a year earlier · market: close on the first session after the filing against the last close before it, S&P 500 over the same session
Quarterly results of PYXS on the consolidated basis with the market's move on the first session after each filing
QuarterRevenue $Revenue YoYProfit $Profit YoYEPS $Market on the day
Jun 2026filed Aug 13——−$25.3M—-0.400.0%S&P 500 −0.2% · +0.2 pp
Mar 2026filed Aug 13——−$23.3M—-0.370.0%S&P 500 −0.2% · +0.2 pp
Dec 2025filed Mar 23——−$18.1M—-0.28—not reached
Sep 2025filed Nov 3——−$22.0M—-0.35—not reached
Jun 2025filed Aug 13$2.8M—−$18.4M—-0.300.0%S&P 500 −0.2% · +0.2 pp
Mar 2025filed Aug 13——−$21.2M—-0.350.0%S&P 500 −0.2% · +0.2 pp
Dec 2024filed Mar 18——−$35.6M—-0.62—not reached
Sep 2024filed Nov 3——−$21.2M—-0.35—not reached
By fiscal yearfiscal years as filed in the 10-K · named by the year the fiscal year ends
Financial-year results of PYXS on the consolidated basis, summed from the quarters filed
YearRevenue $Revenue YoYProfit $Profit YoYEPS $
FY25to Dec 2025$13.9M▼ −14%−$79.6M—-1.28
FY24to Dec 2024$16.1M—−$77.3M—-1.32
FY23to Dec 2023——−$73.8M—-1.85
FY22to Dec 2022——−$120.7M—-3.65
FY21to Dec 2021——−$76.0M—-8.95

Fundamentals

consolidated · filings to Jun 2026 · close $2.33 on Sep 30

17 times book value, market cap $194.3M.

Valuation
Market cap
$194.3Mon Sep 30
Price to earnings
—
Trailing EPS
$-1.40diluted · consolidated · four quarters to Jun 2026
Price to book
17consolidated · balance sheet to Jun 2026
Book value a share
$0.14consolidated · balance sheet to Jun 2026
Debt to equity
—
Return on equity
-180%trailing profit over average equity · consolidated
Dividend yield
—
Price to sales
—
Shares outstanding
83.4Mon Sep 30
Growthsums of the four quarters filed to Jun 2026 · growth against the four quarters before them · consolidated
Revenue, trailing 12 months
—
Revenue growth, 12 months
—
Revenue 3-year CAGR
—trailing twelve months against the twelve months 3 years earlier · consolidated
Profit, trailing 12 months
−$88.7Mfour quarters to Jun 2026
Profit growth, 12 months
—
Profit 3-year CAGR
—

Shareholding

SEC Forms 3, 4 and 5

No open-market insider buying or selling in the last 90 days.

Insider tradesSEC Forms 3, 4 and 5 · the latest 4
PYXS insider trades
InsiderTradeSharesPriceHeld after
HUMPHREY RACHELDirectorsold · Apr 14, 20251,400$0.9795,405
HUMPHREY RACHELDirectorsold · Apr 21, 202513,896$1.0381,309
HUMPHREY RACHELDirectorsold · Apr 17, 2025200$0.9795,205
Wadhane JitendraOfficergranted · Mar 24, 2026109,461$0.00512,882

Corporate actions

exchange records

No corporate action on record for PYXS yet.

Price history

131 sessions on record · to Sep 30 · end of day

PYXS is −32.3% over 20 sessions against the S&P 500's +0.1%, 44% below its 52-week high, realised volatility 120% annualised.

Returns against S&P 500longest window first · S&P 500 over the same sessions
Returns of the stock and S&P 500 over six windows, longest first
WindowFrom $PYXS %S&P 500 %Difference pp
120 sessionssince Apr 9$1.61▲ +45%▲ +12%+33
60 sessionssince Jul 7$3.07▼ −24%▲ +2.0%−26
20 sessionssince Sep 1$3.44▼ −32%▲ +0.11%−32
5 sessionssince Sep 23$3.22▼ −28%▼ −0.67%−27
1 sessionsince Sep 29$2.90▼ −20%▼ −0.21%−19
Averages of the closeclose against each average
5-session average
$2.78close −16% from it
20-session average
$3.27close −29% from it
50-session average
$3.17close −26% from it
Range and volumetrue range over 14 sessions · high to low over 20 · volume against the 20-session average
Average true range, 14
$0.2410% of the close
Average day's range, 20
$0.198.1% of the close
Volume against 20 sessions
8.78×8.15M vs 1.31M average
Volatility and co-movement with S&P 500annualised from daily returns
Realised volatility, 20
120%≈ ±7.3% a session · moved more than that on 5 of 20
Realised volatility, 60
130%≈ ±8.1% a session · moved more than that on 16 of 60
Beta to S&P 500, 60
1.18moved with S&P 500 on 28 of 60 sessions
Up and down sessionscloses above and below the previous close
Last 20 sessions
7 up · 11 downof 18
Last 60 sessions
25 up · 31 downof 56
Best session, 250
▲ +26%May 6
Worst session, 250
▼ −26%Aug 11

Short-sale volume

25 sessions · to Sep 30, 2026

Short sales were 57% of reported volume on Sep 30, 2026, against 56% over the last 25 sessions.

Last 10 sessionsshare of the day's reported volume
PYXS daily short-sale volume
SessionShort volumeReported volumeShort share
Sep 30, 20261.84M3.23M57.0%
Sep 29, 202651.7K75.5K68.6%
Sep 28, 202694.3K164K57.7%
Sep 25, 2026173K297K58.2%
Sep 24, 2026274K454K60.4%
Sep 23, 2026137K226K60.5%
Sep 22, 2026107K210K51.2%
Sep 21, 2026177K271K65.1%
Sep 18, 202691.9K163K56.2%
Sep 17, 2026117K221K52.9%

Filings

SEC EDGAR · newest first
PYXS SEC filings
FiledFormReport date
Sep 9, 20268-KSep 9, 2026
Sep 8, 20264Sep 4, 2026
Sep 8, 20268-KSep 3, 2026
Aug 28, 2026424B2—
Aug 27, 2026EFFECT—
Aug 20, 20264Aug 20, 2026
Aug 20, 2026S-3—
Aug 14, 20264Aug 12, 2026
Aug 13, 202610-QJun 30, 2026
Aug 13, 20268-KAug 13, 2026
Jul 10, 2026SCHEDULE 13G—
Jul 10, 20263Jun 30, 2026
Jul 2, 20264Jun 30, 2026
Jul 2, 20268-KJun 30, 2026
Jul 2, 2026SCHEDULE 13G/A—
Jun 30, 2026144—
Jun 15, 20268-KJun 15, 2026
May 14, 202610-QMar 31, 2026
May 14, 20268-KMay 14, 2026
Apr 30, 2026ARSDec 31, 2025
Apr 30, 2026DEFA14A—
Apr 30, 2026DEF 14AApr 30, 2026
Apr 30, 20268-K/AFeb 6, 2026
Mar 25, 20264Mar 24, 2026
Mar 25, 20264Mar 24, 2026

About Pyxis Oncology, Inc. Common Stock

SEC and exchange records
Company
Pyxis Oncology, Inc. Common Stock
Exchange
XNAS
SEC CIK
1782223
Sessions on record
131
Price source
End of day · delayed
Computed
2 Oct, 01:59 am IST

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